• beat365

    Sofosbuvir

    Category: New Drug for Hepatitis C
    Product Name: Sofosbuvir
    Chemical name: (S)-2-(((2R, 3R, 4R, 5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl) -4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-ylmethoxy)-phosphorylamino)-propionic acid isopropyl ester
    CAS No.: 1190307-88-0; 1064684-44-1
    Molecular Formula: C22H29FN3O9P
    Molecular weight: 529.45
    Specification: 1kg/tin, 5kg/tin
    Standard: enterprise internal control standard

    Detailed introduction

    Property: white powder
    Solubility: slightly soluble in water (pH 1.2 -7.7), freely soluble in ethanol and acetone, soluble in isopropyl ketone, insoluble in heptane.
    Identification: Complies with standard
    Melting point: 118°C - 128°C
    Clarity and colour: The 1% ethanol sample solution is not more intense than the B9 reference solution and the reference suspension II.
    Moisture: ≤0.5%
    Heavy metals: ≤20ppm
    Chiral purity: Rp isomer ≤0.15%
    Related substances: Impurity A≤0.15%, Impurity B≤0.15%, Impurity C≤0.15%, Impurity D≤0.15%, Single impurity ≤0.1%, Total impurities ≤1.0%
    Residual solvents: Tetrahydrofuran ≤0.072%, Methanol ≤0.1%, Acetic acid ≤0.1%, Ethyl acetate ≤0.3%, Dichloromethane ≤0.06%
    Content: 98.0% - 102.0%
    Storage: Protect from light, seal, and stored in a dry place